Sirt1 alleviates LPS induced inflammation of periodontal ligament fibroblasts via downregulation of TLR4

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.8K citations

Education, Genetics, Molecular Biology +12

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.7K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

R. Saravanan, Se‐Ran Yang, Vuokko L. Kinnula et al. · American Journal of Respiratory and Critical Care Medicine · 2008 · 520 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Interactions between Periodontal Bacteria and Human Oral Epithelial Cells: <i>Fusobacterium nucleatum</i> Adheres to and Invades Epithelial Cells

Yiping W. Han, Wenyuan Shi, George T.‐J. Huang et al. · Infection and Immunity · 2000 · 437 citations · Full text

Dentistry, Microbiology, Periodontology +17

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

Se‐Ran Yang, Jessica Wright, Mark R. Bauter et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2006 · 390 citations

Life Sciences, Immunology, Molecular Biology +17