IEEE Journal of Biomedical and Health Informatics · 2018 · 174 citations · 47 references
ComputingComputer ScienceDermatologyComputer VisionDiagnostic ImagingMachine LearningDeep LearningFeature-level FusionImage FusionRepresentation LearningContextual Feature FusionDeep Feature FusionFeature FusionHierarchical Feature FusionLesion SegmentationMultimodal Feature FusionResidual NetworksSkin Lesion Detection
Automatic delineation of skin lesion contours from dermoscopy images is a basic step in the process of diagnosis and treatment of skin lesions. However, it is a challenging task due to the high variation of appearances and sizes of skin lesions. In order to deal with such challenges, we propose a new dense deconvolutional network (DDN) for skin lesion segmentation based on residual learning. Specifically, the proposed network consists of dense deconvolutional layers (DDLs), chained residual pooling (CRP), and hierarchical supervision (HS). First, unlike traditional deconvolutional layers, DDLs are adopted to maintain the dimensions of the input and output images unchanged. The DDNs are trained in an end-to-end manner without the need of prior knowledge or complicated postprocessing procedures. Second, the CRP aims to capture rich contextual background information and to fuse multilevel features. By combining the local and global contextual information via multilevel feature fusion, the high-resolution prediction output is obtained. Third, HS is added to serve as an auxiliary loss and to refine the prediction mask. Extensive experiments based on the public ISBI 2016 and 2017 skin lesion challenge datasets demonstrate the superior segmentation results of our proposed method over the state-of-the-art methods.
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