<i>E</i>-Selective synthesis of vinyl sulfones <i>via</i> silver-catalyzed sulfonylation of styrenes

Abstract

An efficient and highly E-selective protocol for the synthesis of vinyl sulfones is described. This simple protocol demonstrates the first synthesis of vinyl sulfones via a silver-catalyzed C-S bond coupling reaction. In addition, the success of the reaction was found to be critically dependent on the use of TEMPO as the additive.