Inhibition of microRNA-505 suppressed MPP+ -induced cytotoxicity of SHSY5Y cells in an in vitro Parkinson's disease model

Parkinson's disease symptoms: The patient's perspective

Marios Politis, Kit Wu, Sophie Molloy et al. · Movement Disorders · 2010 · 639 citations

Nursing, Neurology, Movement Disorders +16

Regulation of brain mitochondrial H₂O₂ production by membrane potential and NAD(P)H redox state

Anatoly A. Starkov, Gary Fiskum · Journal of Neurochemistry · 2003 · 490 citations

Life Sciences, Biochemistry, Neuroscience +17

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

Elena Miñones-Moyano, Sílvia Porta, Geòrgia Escaramís et al. · Human Molecular Genetics · 2011 · 483 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism

David S. Cassarino, Janice K. Parks, W. Davis Parker et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 1999 · 304 citations

Life Sciences, Biochemistry, Neuroscience +13

Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease

David S. Cassarino, Christopher P. Fall, Russell H. Swerdlow et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 1997 · 265 citations

Life Sciences, Neurobiology, Neuroscience +16