Anesthesia & Analgesia · 2018 · 22 citations · 6 references
MedicinePerioperative MedicineSurgeryDiabetologyPerioperative Outcomes ResearchPerioperative Quality ImprovementDiabetes ManagementDiabetes MellitusGlycemic ControlGlycemic MonitoringHypoglycemia ManagementPerioperative MonitoringBlood Glucose RegulationGlycemic Control After SurgeryOral Hypoglycemic ManagementOral Hypoglycemic TherapyPerioperative Diabetes ManagementPerioperative Glucose ManagementPerioperative Glycemic ManagementPreoperative Glycemic Control
Patients with type 2 diabetes mellitus receiving oral hypoglycemic drugs (OHDs) are usually instructed to stop them before surgery. We hypothesize that continuing OHD preoperatively should result in lower perioperative blood glucose (BG) levels. Ambulatory surgery patients with type 2 diabetes mellitus on OHDs were randomized to continue (n = 69) or withhold (n = 73) OHDs preoperatively. Log-transformed BG levels at pre-, intra-, and postoperative periods were analyzed. Perioperative BG levels were significantly lower (mean, 138 mg/dL; 95% confidence interval, 130-146 mg/dL) in the group that continued versus the group that discontinued OHDs (mean, 156 mg/dL; 95% confidence interval, 146-167 mg/dL; P < .001).
6