Self-assembly/disassembly of giant double-hydrophilic polymersomes at biologically-relevant pH

Sun Hae Ra Shin, Patrick T. McAninch, Ian Henderson, Andrew Gomez, Adrienne C. Greene, Eric C. Carnes, Walter F. Paxton

Chemical Communications · 2018 · 22 citations · 24 references

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Abstract

Self-assembled giant polymer vesicles prepared from double-hydrophilic diblock copolymers, poly(ethylene oxide)-b-poly(acrylic acid) (PEO-PAA) show significant degradation in response to pH changes. Because of the switching behavior of the diblock copolymers at biologically-relevant pH environments (2 to 9), these polymer vesicles have potential biomedical applications as smart delivery vehicles.

References

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