A comparative study of synbiotic as an add-on therapy to standard treatment in patients with aggressive periodontitis

Abstract

CONTEXT: The role of synbiotic in the management of aggressive periodontitis (AP) is not well established. AIM: We designed this study to evaluate the efficacy and safety of synbiotic as an add-on therapy in the management of AP. SETTINGS AND DESIGN: This was a randomized, double-blind, placebo-controlled study. MATERIALS AND METHODS: weeks. STATISTICAL ANALYSIS USED: -test. Pearson's Chi-square test was applied to measure gingival bleeding index. RESULTS: < 0.01) in probing depth, clinical attachment loss, oral hygiene index, and bleeding on probing in study group. No Adverse drug reactions were noted. CONCLUSION: Co-administration of synbiotic lozenge along with standard therapy is highly efficacious in improving periodontal health in patients with AP.