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Activated Nitriles in Heterocyclic Synthesis: The Reaction of Cinnamonitrile Derivatives with Active Methylene Reagents
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1983
Year
Derivative (Chemistry)EngineeringHeterocyclicOrganic ChemistryCinnamonitrile DerivativesActive Methylene ReagentsCatalysisPyran DerivativesChemistryPrepared CompoundsHeterocycle ChemistryPharmacologyChemical DerivativeSynthetic ChemistryActivated NitrilesNatural Product Synthesis
Abstract The reaction of substituted cinnamonitrile derivatives with cyanoacetanilide and ethyl acetoacetate is reported. Several new polyfunctional pyridine and pyran derivatives could be synthesised. The structures of the prepared compounds and the mechanisms of their formation is reported.