Concepedia

Immediate and Short-Term Cellular and Biochemical Responses to Pulmonary Single-Dose Studies of Insulin and H-MAP

Lucila Garcia‐Contreras, Donald Sarubbi, Elizabeth Flanders, Doris O'Toole, John E. Smart, Christian E. Newcomer, Anthony J. Hickey

Pharmaceutical Research · 2001 · 22 citations · 23 references

DOI

Concepts

References

23

Large Porous Particles for Pulmonary Drug Delivery

David A. Edwards, Justin Hanes, Giovanni Caponetti et al. · Science · 1997 · 1.2K citations

, , +17

Oral insulin delivery1Abbreviations: GI, gastrointestinal; IDDM, insulin-dependent diabetes mellitus; IU, international units; NIDDM, non-insulin-dependent diabetes mellitus; PIN, phase inversion nanoencapsulation; ZOT, zona occludens toxin.1

Gerardo Carino, Edith Mathiowitz · Advanced Drug Delivery Reviews · 1999 · 343 citations

, , +11

Inhaled insulin1Abbreviations: DM, diabetes mellitus; AIDs, acquired immune deficiency syndrome; SC, subcutaneous; DCCT, Diabetes Control and Complications Trial; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus; i.v., intravenous; DDPC, di-decanoyl-alpha-phosphatidylcholine; AUC, area under the curve; INH, inhaled; Cmax, maximum serum concentration; Cmin, minimum serum concentration; Tmax, time of maximum serum concentration; NS, not significant; HbA1c, hemoglobin A1c; OA, oral agent; SD, standard deviation; MDI, metered dose inhaler; DPI, dry powder inhaler; MMAD, mass median aerodynamic diameter; CMC, critical micelle concentration; SR, sustained release; PLGA, poly lactic acid-co-glycolic acid; GI, gastrointestinal, GSD, geometric standard deviation; TLC, total lung capacity; VC, vital capacity; SMK, smokers; MW, molecular weight; MP, melting point.1

John S. Patton, Julie Bukar, Sudha Nagarajan · Advanced Drug Delivery Reviews · 1999 · 193 citations

, , +12

Insulin Across Respiratory Mucosae by Aerosol Delivery

Frederick M. Wigley, Javier H. Londono, Scott H Wood et al. · Diabetes · 1971 · 175 citations

, , +16

The Pharmacokinetics of Pulmonary-Delivered Insulin: A Comparison of Intratracheal and Aerosol Administration to the Rabbit

Paul Colthorpe, Stephen J. Farr, Glyn Taylor et al. · Pharmaceutical Research · 1992 · 123 citations

, , +12