Publication | Closed Access
Synthesis and antimicrobial activity of some novel furyl and benzimidazole substituted benzyl ethers
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Citations
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References
2007
Year
Organic ChemistryAntimicrobial ChemotherapyChemistryPharmaceutical ChemistryDrug ResistanceS AureusBenzyl EthersAntimicrobial ResistanceAntimicrobial Drug DiscoveryDerivativesAntifungal AgentsAntibacterial AgentAntimicrobial CompoundPharmacologyAntifungal AgentAntibioticsNovel FurylAntimicrobial ActivityMicrobiologyAntimicrobial PharmacodynamicsMedicineS. AureusDrug Discovery
Abstract magnified image In this study, a series of novel furyl and benzimidazole substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against S. aureus , Methicillin resistant S. aureus (MRSA), E. coli, C. albicans and C. krusei. Compound 6f and 6h exhibited the most potent anti‐bacterial activity with lowest MIC values of 3.12 μg/mL against S aureus and MRSA , respectively.
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