Concepedia

GMP Production and Scale-Up of Adherent Neural Stem Cells with a Quantum Cell Expansion System

Revathiswari Tirughana, Marianne Z. Metz, Zhongqi Li, Christine Hall, David S. Hsu, Jim Beltzer, Alexander J. Annala, Diana Oganesyan, Margarita Gutova, Karen S. Aboody

Molecular Therapy — Methods & Clinical Development · 2018 · 35 citations · 24 references

DOIFull text

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Concepts

Abstract

over 6 weeks in CellStacks. We also adenovirally transduced our NSCs within the QCE. We found the QCE system enabled rapid cell expansion and increased yield while maintaining cell properties and reducing process time, labor, and costs with improved efficiency and reproducibility.

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