Concepedia

Publication | Open Access

SMAD4 Prevents Flow Induced Arteriovenous Malformations by Inhibiting Casein Kinase 2

DOIFull Paper Access

125

Citations

39

References

2018

Year

Roxana Ola, Sandrine H. Künzel, Feng Zhang, Gaël Genet, Raja Chakraborty, Laurence Pibouin-Fragner, Kathleen A. Martin, William C. Sessa, Alexandre Dubrac, Anne Eichmann
Circulation

Abstract

Our study reveals SMAD4 as an essential effector of BMP9-10/ALK1 signaling that affects AVM pathogenesis via regulation of CK2 expression and PI3K/AKT1 activation.

References

YearCitations

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