Clinical significance of <scp>PDEF</scp> factor expression and its relation to androgen receptor in <scp>ER</scp>⁻ breast cancer

Abstract

PDEF is associated with markers of bad prognosis, supporting its role as a growth promoter in ER^- BC. Our findings also provide evidence that PDEF is strongly correlated with AR expression in ER^- breast cancer; it may be a downstream target gene of AR and a potential prognostic factor in ER^- BC.