Dissociated Oxygen Consumption and Carbon Dioxide Production in the Post–Cardiac Arrest Rat: A Novel Metabolic Phenotype

Abstract

CA altered cellular metabolism resulting in increased VO₂ with normal VCO₂. Normal VCO₂ suggests that the postresuscitation Krebs cycle is operating at a presumably healthy rate. Increased VO₂ in the face of normal VCO₂ suggests a significant alteration in O₂ utilization in postresuscitation. Several RQ values fell well outside the normally cited range of 0.7 to 1.0. Higher FIO₂ may increase VO₂, leading to even lower RQ values.