A predictive model for conversion to psychosis in clinical high-risk patients

Adam Ciarleglio, Gary Brucato, Michael D. Masucci, Rebecca Altschuler, Tiziano Colibazzi, Cheryl M. Corcoran, Francesca M. Crump, Guillermo Horga, Eugénie Lehembre-Shiah, Wei Leong,

Psychological Medicine · 2018 · 50 citations · 30 references

DOIFull text

Open access

Abstract

The prediction model performed well in classifying converters and non-converters and revealed SIPS measures that are relatively strong predictors of conversion, comparable with the risk calculator published by NAPLS (c-index = 0.71), but requiring only a structured clinical interview. Future work will seek to externally validate the model and enhance its performance with the incorporation of relevant biomarkers.

References

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