MRI Image Segmentation Using Conditional Spatial FCM Based on Kernel-Induced Distance Measure

Abstract

Fuzzy C-means (FCM) clustering is the widest spread clustering approach for medical image segmentation because of its robust characteristics for data classification. But, it does not fully utilize the spatial information and is therefore very sensitive to noise and intensity inhomogeneity in magnetic resonance imaging (MRI). In this paper, we propose a conditional spatial kernel fuzzy C-means (CSKFCM) clustering algorithm to overcome the mentioned problem. The approach consists of two successive stages. First stage is achieved through the incorporation of local spatial interaction among adjacent pixels in the fuzzy membership function imposed by an auxiliary variable associated with each pixel. The variable describes the involvement level of each pixel for construction of membership functions and different clusters. Then, we adapted a kernel-induced distance to replace the original Euclidean distance in the FCM, which is shown to be more robust than FCM. The problem of sensitivity to noise and intensity inhomogeneity in MRI data is effectively reduced by incorporating a kernel-induced distance metric and local spatial information into a weighted membership function. The experimental results show that the proposed algorithm has advantages in accuracy and robustness against noise in comparison with the FCM, SFCM and CSFCM methods on MRI brain images.