Concepedia

Hydrocortisone Affects Fatigue and Physical Functioning Through Metabolism of Tryptophan: A Randomized Controlled Trial

Freek J. H. Sorgdrager, Jorien Werumeus Buning, Elske H. Bos, André P. van Beek, Ido P. Kema

The Journal of Clinical Endocrinology & Metabolism · 2018 · 14 citations · 35 references

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Abstract

Metabolism of tryptophan through the kynurenine pathway is reduced after a 10-week treatment with a higher dose HC and plays a role in the effect of HC on fatigue and physical functioning in patients with secondary AI.

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