The Analyst · 2018 · 40 citations · 41 references
A H2O2-responsive fluorescent chemosensor (CNBE) with a ratiometric emission signal was elaborately designed and synthesized. The ratio signal of the chemosensor was manipulated by an interplaying ICT-activated FRET mechanism. The ratiometric fluorescence imaging was successfully applied to detect H2O2 using CNBE in living cells and zebrafish.
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H <sub>2</sub> O <sub>2</sub> , a Necessary Evil for Cell Signaling
Sue Goo Rhee · Science · 2006 · 2.1K citations
FRET-Based Small-Molecule Fluorescent Probes: Rational Design and Bioimaging Applications
Lin Yuan, Weiying Lin, Kaibo Zheng et al. · Accounts of Chemical Research · 2013 · 976 citations