Diosgenin Attenuates Lipopolysaccharide-Induced Parkinson’s Disease by Inhibiting the TLR/NF-κB Pathway

Bingyu Li, Pengli Xu, Shuyan Wu, Zhixian Jiang, Zhijian Huang, Qian Li, Danhong Chen

Journal of Alzheimer s Disease · 2018 · 57 citations · 23 references

Abstract

Diosgenin had a beneficial effect in LPS-induced rat PD models, by suppressing the TLR/NF-κB signaling pathway. Environmental enrichment could play a synergistic effect with diosgenin, by enhancing the inhibitory effect of diosgenin on the TLR/ NF-κB signaling pathway.

References

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