Journal of Alzheimer s Disease · 2018 · 57 citations · 23 references
Diosgenin had a beneficial effect in LPS-induced rat PD models, by suppressing the TLR/NF-κB signaling pathway. Environmental enrichment could play a synergistic effect with diosgenin, by enhancing the inhibitory effect of diosgenin on the TLR/ NF-κB signaling pathway.
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Microglial Activation and Chronic Neurodegeneration
Melinda E. Lull, Michelle L. Block · Neurotherapeutics · 2010 · 1K citations · Full text
TLR Signaling Tailors Innate Immune Responses in Human Microglia and Astrocytes
Carolyn Jack, Nathalie Arbour, Joshua S. Manusow et al. · The Journal of Immunology · 2005 · 717 citations · Full text