Concepedia

Comparison of topical tofacitinib and 0.1% hypochlorous acid in a murine atopic dermatitis model

Tomoki Fukuyama, Sarah Ehling, Jenny Wilzopolski, Wolfgang Bäumer

BMC Pharmacology and Toxicology · 2018 · 17 citations · 9 references

DOIFull text

Open access

Abstract

These data indicate a similar beneficial potential of topical high dose PR022 HOCl (0.1%) in gel and tofacitinib, in a translational murine model of atopic dermatitis.

References

9

The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

Sarah R. Wilson, Lydia Thé, Lyn Batia et al. · Cell · 2013 · 937 citations · Full text

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Topical tofacitinib for atopic dermatitis: a phase <scp>II</scp> a randomized trial

Robert Bissonnette, Kim Papp, Yves Poulin et al. · British Journal of Dermatology · 2016 · 408 citations · Full text

Histamine H1, H3 and H4 receptors are involved in pruritus

Christina Nassenstein, Maria Gschwandtner, David Schnell et al. · Neuroscience · 2011 · 147 citations

, , +5

Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis

Tomoki Fukuyama, Sarah Ehling, Elizabeth H. Cook et al. · Journal of Pharmacology and Experimental Therapeutics · 2015 · 99 citations

Translational Animal Models of Atopic Dermatitis for Preclinical Studies.

Britta C. Martel, Paola Lovato, Wolfgang Bäumer et al. · PubMed · 2017 · 74 citations

, , +9