Physicochemical characterization of inorganic deposits associated with granulomas in cutaneous sarcoidosis

Abstract

This study emphasizes the need of using combined methods for assessment of mineral deposits in granulomatous diseases. According to the location and characteristics of deposits, we can hypothesize that SiO₂ particles contribute to the granuloma formation, whereas CaCO₃ deposits are related to the granuloma biology. However, the significance of the association between SiO₂ deposits and sarcoidosis is still disputed.