RA190, a Proteasome Subunit ADRM1 Inhibitor, Suppresses Intrahepatic Cholangiocarcinoma by Inducing NF-KB-Mediated Cell Apoptosis - Concepedia

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RA190, a Proteasome Subunit ADRM1 Inhibitor, Suppresses Intrahepatic Cholangiocarcinoma by Inducing NF-KB-Mediated Cell Apoptosis

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References

2018

Year

Guangyang Yu, Xuan Wang, Su-Su Zheng, Xiaomei Gao, Qingan Jia, Wenwei Zhu, Lu Lu, Hu‐Liang Jia, Jinhong Chen, Qiongzhu Dong,

Cellular Physiology and Biochemistry

Abstract

Our findings indicate that up-regulated ADRM1 was involved in ICC progression and suggest the potential clinical application of ADRM1 inhibitors (e.g., RA190 and KDT-11) for ICC treatment.