Concepedia

Design, synthesis and evaluation of novel bivalent β-carboline derivatives as multifunctional agents for the treatment of Alzheimer's disease

Yifan Zhao, Feng Ye, Jian Xu, Qinghong Liao, Lei Chen, Weijia Zhang, Haopeng Sun, Wenyuan Liu, Feng Feng, Wei Qu

Bioorganic & Medicinal Chemistry · 2018 · 36 citations · 33 references

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Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

Nigel H. Greig, Tadanobu Utsuki, Donald K. Ingram et al. · Proceedings of the National Academy of Sciences · 2005 · 723 citations · Full text

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Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine

M.‐Marsel Mesulam, Angela L. Guillozet, Pamela L Shaw et al. · Neuroscience · 2002 · 651 citations

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Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex

Mubeen A. Ansari, Stephen W. Scheff · Journal of Neuropathology & Experimental Neurology · 2010 · 599 citations · Full text

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CHANGES IN BRAIN CHOLINESTERASES IN SENILE DEMENTIA OF ALZHEIMER TYPE

Elaine K. Perry, R. H. Perry, G. Blessed et al. · Neuropathology and Applied Neurobiology · 1978 · 555 citations

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Highly Potent, Selective, and Low Cost Bis-tetrahydroaminacrine Inhibitors of Acetylcholinesterase

Yuan‐Ping Pang, Polly A. Quiram, Tanya M. Jelacic et al. · Journal of Biological Chemistry · 1996 · 346 citations · Full text

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