Differential antibacterial control by neutrophil subsets

Pieter H. C. Leliefeld, Janesh Pillay, Nienke Vrisekoop, Marjolein Heeres, Tamar Tak, Matthijs Kox, Suzan H. M. Rooijakkers, Taco W. Kuijpers, Peter Pickkers, Luke P. H. Leenen,

Blood Advances · 2018 · 107 citations · 47 references

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Abstract

-banded neutrophils were the only neutrophil subset that adequately contained MRSA. These findings demonstrate a clear neutrophil heterogeneity in their antimicrobial capacity and the appearance of neutrophil subsets with a clear differentiation in functionality during acute inflammation. Furthermore, this study provides an evolutionary basis for the rapid release of banded neutrophils into the circulation during acute inflammation.

References

47