Concepedia

Catalytic enantioselective α-sulfenylation of β-ketocarbonyls by chiral primary amines

Linfeng Cui, Yang’en You, Xueling Mi, Sanzhong Luo

Organic Chemistry Frontiers · 2018 · 26 citations · 38 references

DOI

Concepts

Abstract

A simple chiral primary amine catalyst was identified to enable effective catalysis in direct α-sulfenylation of acyclic and cyclic β-ketocarbonyls with good yields and excellent enantioselectivities.

References

38

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Paolo Melchiorre, Mauro Marigo, Armando Carlone et al. · Angewandte Chemie International Edition · 2008 · 1.3K citations

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Enantioselective Organocatalyzed α Sulfenylation of Aldehydes

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The Diarylprolinol Silyl Ether System: A General Organocatalyst

Kim L. Jensen, Gustav Dickmeiss, Hao Jiang et al. · Accounts of Chemical Research · 2011 · 740 citations

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A General Organocatalyst for Direct α-Functionalization of Aldehydes:  Stereoselective C−C, C−N, C−F, C−Br, and C−S Bond-Forming Reactions. Scope and Mechanistic Insights

Johan Franzén, Mauro Marigo, Doris Fielenbach et al. · Journal of the American Chemical Society · 2005 · 633 citations

, , +16

Cinchona‐based Primary Amine Catalysis in the Asymmetric Functionalization of Carbonyl Compounds

Paolo Melchiorre · Angewandte Chemie International Edition · 2012 · 439 citations

, , +15