CCR5: Established paradigms and new frontiers for a ‘celebrity’ chemokine receptor

Identification of a major co-receptor for primary isolates of HIV-1

Hongkui Deng, Rong Liu, Wilfried Ellmeier et al. · Nature · 1996 · 3.7K citations

Life Sciences, Infectious Diseases, Molecular Biology +11

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

Tatjana Dragic, Virginia Litwin, Graham P. Allaway et al. · Nature · 1996 · 3.2K citations

Life Sciences, Immunology, Molecular Biology +14

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

Rong Liu, William A. Paxton, Sunny Choe et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Infectious Diseases +13

The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints

Robert Fredriksson, Malin C. Lagerström, Lars‐Gustav Lundin et al. · Molecular Pharmacology · 2003 · 2.9K citations

Life Sciences, Genetics, Molecular Biology +13

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Michel Samson, Frédérick Libert, Benjamin J. Doranz et al. · Nature · 1996 · 2.9K citations

Life Sciences, Genetics, Molecular Genetics +11