Denosumab-Associated Severe Hypocalcemia in a Patient With Chronic Kidney Disease

A study of the biological receptor activator of nuclear factor-kappaB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer.

Jean-Jacques Body, Thierry Façon, Robert E. Coleman et al. · Clinical Cancer Research · 2006 · 491 citations · Full text

Medicine, Oncology, Pharmacology +17

A Phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases

Jean‐Jacques Body, Philip R. Greipp, Robert E. Coleman et al. · Cancer · 2003 · 381 citations · Full text

Medicine, Oncology, Pharmacology +17

Effects of denosumab on fracture and bone mineral density by level of kidney function

Sophie A. Jamal, Östen Ljunggren, Catherine Stehman‐Breen et al. · Journal of Bone and Mineral Research · 2011 · 352 citations

Medicine, Clinical Sciences, Nephrology +14

Hypocalcaemia in patients with metastatic bone disease treated with denosumab

Jean-Jacques Body, Henry G. Bone, Richard H. De Boer et al. · European Journal of Cancer · 2015 · 150 citations · Full text

Medicine, Oncology, Pharmacotherapy +15

Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts.

Karim Fizazi, Jun Yang, Sara Peleg et al. · PubMed · 2003 · 146 citations

Medicine, Cancer Biology, Oncology +17