Palladium‐Catalyzed Hydroalkylation of Alkynes with Cyclopropanols: Access to γ,δ‐Unsaturated Ketones

Abstract

Abstract A palladium‐catalyzed hydroalkylation of alkynes with cyclopropanols has been developed. This reaction provided a straightforward way to the synthesis of γ,δ‐unsaturated ketones in moderate to good yields, exhibiting high atom economy and Z/E selectivity. Deuterated tri‐substituted alkenes could also be expediently produced by using deuterium oxide as a co‐solvent. magnified image