Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice

Amel Dudakovic, Emily T. Camilleri, Christopher R. Paradise, Rebekah M. Samsonraj, Martina Gluscevic, Carlo Alberto Paggi, Dana L. Begun, Farzaneh Khani, Oksana Pichurin, Farah S. Ahmed,

Journal of Biological Chemistry · 2018 · 85 citations · 53 references

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Abstract

serves a bifunctional role during bone formation by suppressing osteogenic lineage commitment while simultaneously facilitating proliferative expansion of osteoprogenitor cells.

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