Concepedia

Publication | Closed Access

High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics

DOI

39

Citations

45

References

2018

Year

Xiaoxuan Yang, Youssef Jounaïdi, Jennifer Dai, Francisco Marte-Oquendo, Elizabeth S. Halpin, Lauren E. Brown, Richard Trilles, Wenqing Xu, Renee V. Daigle, Buwei Yu,
Anesthesiology

Abstract

Photomotor response assays in zebrafish larvae are a mechanism-independent platform for high-throughput screening to identify novel sedative-hypnotics. The variety of chemotypes producing hypnosis is likely much larger than currently known.

References

YearCitations

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