StatPearls · 2019 · 34 citations · 1 references
MedicinePharmacologyPharmacotherapyClinical PharmacologyDiabetologyMetabolic RegulationDiabetes ControlDiabetes ManagementDiabetes MellitusGlycemic ControlGlycemic MonitoringHypoglycemia ManagementGlycemic Control OptimizationGlycemic TargetsMetabolic TherapiesOral Hypoglycemic ManagementOral Hypoglycemic TherapyPancreatic Beta-cell FunctionPancreatic Beta-cell SecretionType 2 Diabetes Mellitus Treatment
The most effective management of diabetes mellitus demands an interprofessional approach involving both lifestyle modifications with diet and exercise and pharmacologic therapies as necessary to meet individualized glycemic goals. Lifestyle modifications must be combined with oral pharmacologic agents for optimal glycemic control, particularly as type 2 diabetes mellitus progresses with continued loss of pancreatic beta-cell function and insulin production. This activity outlines the indications, mechanisms of action, methods of administration, significant adverse effects, contraindications, monitoring, and toxicity of oral hypoglycemic medications, so providers can direct patient therapy to optimal outcomes where glycemic control and diabetes play a role in outcomes.
1