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The anti-malarial atovaquone selectively increases chemosensitivity in retinoblastoma via mitochondrial dysfunction-dependent oxidative damage and Akt/AMPK/mTOR inhibition

Medicinal ChemistryBiochemistryMitochondrial FunctionMedicineNatural SciencesLipid PeroxidationCell DeathAnti-malarial AtovaquoneAkt/ampk/mtor InhibitionReactive Oxygen SpeciePharmacologyRedox BiologyOxidative Stress