Concepedia

Intermolecular autocatalytic activation of serine protease zymogen factor C through an active transition state responding to lipopolysaccharide

Toshio Shibata, Yuki Kobayashi, Yuto Ikeda, Shun-ichiro Kawabata

Journal of Biological Chemistry · 2018 · 17 citations · 33 references

DOIFull text

Open access

Concepts

Abstract

site or by acting as a scaffold to induce specific protein-protein interactions between factor C* molecules.

References

33

Structural basis of the activation and action of trypsin

Robert Huber, Wolfram Bode · Accounts of Chemical Research · 1978 · 673 citations

, , +6

Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

Stephan T. Freer, J. Kraut, Jon D. Robertus et al. · Biochemistry · 1970 · 345 citations

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The American horseshoe crab

Choice Reviews Online · 2004 · 265 citations

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Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Rainer W. Friedrich, Peter Panizzi, Pablo Fuentes‐Prior et al. · Nature · 2003 · 260 citations

, , +9

The ancient origin of the complement system

Yong Zhu, Saravanan Thangamani, Bow Ho et al. · The EMBO Journal · 2004 · 251 citations · Full text

, , +9