Concepedia

Succinic semialdehyde dehydrogenase deficiency: The combination of a novel ALDH5A1 gene mutation and a missense SNP strongly affects SSADH enzyme activity and stability

Giovanna Menduti, Elisa Biamino, Roberta Vittorini, Serena Vesco, Maria Paola Puccinelli, Francesco Porta, Concetta Capo, Bianca Maria Ciminelli, Federico Iacovelli, Marco Spada,

Molecular Genetics and Metabolism · 2018 · 19 citations · 21 references

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21

UCSF Chimera—A visualization system for exploratory research and analysis

Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Journal of Computational Chemistry · 2004 · 47.8K citations

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The FoldX web server: an online force field

Joost Schymkowitz, Jean‐Paul Borg, François Stricher et al. · Nucleic Acids Research · 2005 · 2.9K citations · Full text

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How Protein Stability and New Functions Trade Off

Nobuhiko Tokuriki, François Stricher, Luís Serrano et al. · PLoS Computational Biology · 2008 · 610 citations · Full text

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Clinical spectrum of succinic semialdehyde dehydrogenase deficiency

Phillip L. Pearl, K. Michael Gibson, Maria T. Acosta et al. · Neurology · 2003 · 210 citations

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Stability-activity tradeoffs constrain the adaptive evolution of RubisCO

Romain A. Studer, Pascal‐Antoine Christin, Mark A. Williams et al. · Proceedings of the National Academy of Sciences · 2014 · 191 citations · Full text

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