Allylic Arylation of 1,3-Dienes via Hydroboration/Migrative Suzuki–Miyaura Cross-Coupling Reactions

Abstract

The hydroboration/Pd-catalyzed migrative Suzuki–Miyaura cross-coupling of 1,3-dienes with electron-deficient aryl halides has been developed, which enables the synthesis of branched allylarenes directly from primary homoallylic alkyl boranes. A ligand-tuned linear- or branch-selective coupling for these aryl halides has also been achieved.