Metabolic engineering of Corynebacterium glutamicum for efficient production of succinate from lignocellulosic hydrolysate

Abstract

This work introduces an efficient process for the bioconversion of biomass into succinate using a thoroughly engineered strain of <i>C. glutamicum</i>. To the best of our knowledge, this is the highest titer of succinate produced from non-food lignocellulosic feedstock, which highlights that the biosafety level 1 microorganism <i>C. glutamicum</i> is a promising platform for the envisioned lignocellulosic biorefinery.