Nature Communications · 2018 · 167 citations · 47 references
PharmacyToxicologyBiosensorsForensic ToxicologySensorsChemical SensorsDrug DiscriminationDrug IdentificationFluorescence SpectroscopySensor-based AnalysisToxicological Drug ScreeningAmino AcidsChemical SensingContact DetectionContact IdentificationFluorescence-based SensingFluorescent SensorsIllicit Drug DetectionSensitivity
Abstract Sensitive and rapid identification of illicit drugs in a non-contact mode remains a challenge for years. Here we report three film-based fluorescent sensors showing unprecedented sensitivity, selectivity, and response speed to the existence of six widely abused illicit drugs, including methamphetamine (MAPA), ecstasy, magu, caffeine, phenobarbital (PB), and ketamine in vapor phase. Importantly, for these drugs, the sensing can be successfully performed after 5.0 × 10 5 , 4.0 × 10 5 , 2.0 × 10 5 , 1.0 × 10 5 , 4.0 × 10 4 , and 2.0 × 10 2 times dilution of their saturated vapor with air at room temperature, respectively. Also, presence of odorous substances (toiletries, fruits, dirty clothes, etc.), water, and amido-bond-containing organic compounds (typical organic amines, legal drugs, and different amino acids) shows little effect upon the sensing. More importantly, discrimination and identification of them can be realized by using the sensors in an array way. Based upon the discoveries, a conceptual, two-sensor based detector is developed, and non-contact detection of the drugs is realized.
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An optoelectronic nose for the detection of toxic gases
Sung Hee Lim, Liang Feng, Jonathan W. Kemling et al. · Nature Chemistry · 2009 · 476 citations · Full text
Ryuhei Furue, Takuro Nishimoto, In Seob Park et al. · Angewandte Chemie International Edition · 2016 · 456 citations