MSCs protect endothelial cells from inflammatory injury partially by secreting STC1

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

Ryang Hwa Lee, Min Jeong Seo, Daniel J. Kota et al. · Cell stem cell · 2009 · 1.9K citations · Full text

Inflammation, Thrombosis, Cytokine +10

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

Thomas J. Bartosh, Joni Ylöstalo, Arezoo Mohammadipoor et al. · Proceedings of the National Academy of Sciences · 2010 · 945 citations

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages

Hosoon Choi, Ryang Hwa Lee, Nikolay Bazhanov et al. · Blood · 2011 · 636 citations · Full text

Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment

Yoshitaka Iso, Jeffrey L. Spees, Claudia Serrano et al. · Biochemical and Biophysical Research Communications · 2007 · 398 citations · Full text

Regenerative Medicine, Cardiac Function, Cell Therapy +14

Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action

Lavinia Ionescu, Roisin Byrne, Tim van Haaften et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2012 · 322 citations · Full text

Acute Lung Injury, Inflammatory Lung Disease, Lung Inflammation +18