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The Effect of Culture Temperature on the Aggregation of Recombinant TNFR-Fc is Regulated by the PERK-eIF2a Pathway in CHO Cells

DOI

14

Citations

0

References

2018

Year

Kai Wang, Tu Zhang, Jing Chen, Chenxuexuan Liu, Jie Tang, Qiuling Xie
Protein and Peptide Letters

Abstract

Culture temperature affects TNFR-Fc folding and secretion. Protein aggregation was partly reduced in a PERK-dependent way at 31°C.