Application of a Nanotechnology-Based, Point-of-Care Diagnostic Device in Diabetic Kidney Disease

Abstract

A nanotechnology-based PoC device for quantitative measurement of HbA_1c, hemoglobin, serum albumin, microalbuminuria, and the urine albumin-to-creatinine ratio was developed for detection of early DKD and showed excellent correlation between the device and laboratory results. This device has the potential for early detection of DM and/or DKD, especially in remote communities in underserved areas of the world where prevalence of diabetes is rapidly increasing.