Concepedia

Ceragenins are active against drug-resistant Candida auris clinical isolates in planktonic and biofilm forms

M Hashemi, John Rovig, Brett Holden, Maddison Taylor, Scott Weber, John T. Wilson, Brian Hilton, Aaron L. Zaugg, Samuel W Ellis, Connor D Yost,

Journal of Antimicrobial Chemotherapy · 2018 · 36 citations · 43 references

DOIFull text

Open access

Abstract

Ceragenins demonstrated activity against C. auris, suggesting that these compounds warrant further study to determine whether they can be used for topical applications to skin and mucosal tissues for treatment of infections with C. auris and other fungi.

References

43

Simultaneous Emergence of Multidrug-Resistant <i>Candida auris</i> on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

Shawn R. Lockhart, Kizee A. Etienne, Snigdha Vallabhaneni et al. · Clinical Infectious Diseases · 2016 · 1.6K citations · Full text

The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation

Emily L. Larkin, Christopher Hager, Jyotsna Chandra et al. · Antimicrobial Agents and Chemotherapy · 2017 · 378 citations · Full text

Candida auris candidaemia in Indian ICUs: analysis of risk factors

Shivaprakash M. Rudramurthy, Arunaloke Chakrabarti, Raees A. Paul et al. · Journal of Antimicrobial Chemotherapy · 2017 · 335 citations · Full text

Comparison of EUCAST and CLSI Reference Microdilution MICs of Eight Antifungal Compounds for Candida auris and Associated Tentative Epidemiological Cutoff Values

Maiken Cavling Arendrup, Anupam Prakash, Joseph Meletiadis et al. · Antimicrobial Agents and Chemotherapy · 2017 · 259 citations · Full text

Ceragenins: Cholic Acid-Based Mimics of Antimicrobial Peptides

Xin-Zhong Lai, Yanshu Feng, Jacob Pollard et al. · Accounts of Chemical Research · 2008 · 206 citations

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