Striatal dopamine regulates systemic glucose metabolism in humans and mice

Kasper W. ter Horst, Nicolette M. Lammers, Richard Trinko, Darren M. Opland, Martijn Figee, Mariëtte T. Ackermans, Jan Booij, Pepijn van den Munckhof, P. Richard Schuurman, Eric Fliers,

Science Translational Medicine · 2018 · 108 citations · 55 references

Concepts

Abstract

receptor-expressing neurons in the nucleus accumbens increased glucose tolerance and insulin sensitivity in mice. Together, these findings support the hypothesis that striatal neuronal activity regulates systemic glucose metabolism.

References

55