The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

Claudio Rivera, Juha Voipio, John A. Payne, +6

Nature

Synaptic PlasticityNeuronal MaturationHyperpolarization (Biology)NeurophysiologySynaptic Transmission +11

Neocortical Network Activity<i>In Vivo</i>Is Generated through a Dynamic Balance of Excitation and Inhibition

Bilal Haider, Alvaro Duque, Andrea R. Hasenstaub, +1

Journal of Neuroscience

Disruption of KCC2 Reveals an Essential Role of K-Cl Cotransport Already in Early Synaptic Inhibition

Christian A. Hübner, Valentin Stein, Irm Hermans‐Borgmeyer, +3

Neuron

Molecular Cloning and Functional Expression of the K-Cl Cotransporter from Rabbit, Rat, and Human

Christopher M. Gillen, Susan Brill, John A. Payne, +1

Journal of Biological Chemistry

Molecular BiologyCellular PhysiologyCell SignalingCell PhysiologyProtein Function +17

GABA in the mammalian suprachiasmatic nucleus and its role in diurnal rhythmicity

Shlomo Wagner, Mona Castel, Harold Gainer, +1

Nature

Neurobiological MechanismMammalian Suprachiasmatic NucleusNeurophysiologyNeuroanatomyMedicine +10

A GABAergic Mechanism Is Necessary for Coupling Dissociable Ventral and Dorsal Regional Oscillators within the Circadian Clock

H. Albus, Mariska J. Vansteensel, Stephan Michel, +2

Current Biology

Neurobiological MechanismNeural MechanismNeurophysiologyMedicineBrain Mechanism +10

A randomised controlled trial of bumetanide in the treatment of autism in children

Éric Lemonnier, Céline Degrez, M Phelep, +5

Translational Psychiatry

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor–mediated currents

Henry H.C. Lee, Tarek Z. Deeb, Joshua Walker, +2

Nature Neuroscience

Synaptic PlasticitySignal TransductionMolecular PhysiologyBiochemistryNeurophysiology +11

Seasonal Encoding by the Circadian Pacemaker of the SCN

Henk Tjebbe vanderLeest, Thijs Houben, Stephan Michel, +5

Current Biology

SleepAlertnessNeurophysiologyMedicinePhysiology +8

Bumetanide for the treatment of seizures in newborn babies with hypoxic ischaemic encephalopathy (NEMO): an open-label, dose finding, and feasibility phase 1/2 trial

Ronit Pressler, Geraldine B. Boylan, Neil Marlow, +17

The Lancet Neurology

NeonatologyPediatric HydrocephalusHypoxic Ischaemic EncephalopathyPediatricsNeuropharmacology +5