A cocktail of ¹⁶⁵Er(<scp>iii</scp>) and Gd(<scp>iii</scp>) complexes for quantitative detection of zinc using SPECT and MRI

Abstract

We propose quantitative assessment of zinc by combining nuclear and MR imaging. We use a cocktail of a Gd3+-complex providing a Zn2+-dependent MRI response and its 165Er3+ analogue allowing for concentration assessment. 165Er is readily obtained in a cyclotron and purified, which is indispensable for successful quantification of metal ions.