Fungal cytochrome P450 protein Cyp51: What we can learn from its evolution, regulons and Cyp51-based azole resistance

Active genes are tri-methylated at K4 of histone H3

Helena Santos-Rosa, Robert Schneider, Andrew J. Bannister et al. · Nature · 2002 · 2.2K citations

Life Sciences, Molecular Biology, Molecular Genetics +11

Frequency and Evolution of Azole Resistance in<i>Aspergillus fumigatus</i>Associated with Treatment Failure1

Susan J. Howard, Daša Cerar, Michael J. Anderson et al. · Emerging infectious diseases · 2009 · 749 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Cholesterol Addition to ER Membranes Alters Conformation of SCAP, the SREBP Escort Protein that Regulates Cholesterol Metabolism

Andrew J. Brown, Liping Sun, Jamison D. Feramisco et al. · Molecular Cell · 2002 · 417 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

Sven D. Willger, Srisombat Puttikamonkul, Kwang‐Hyung Kim et al. · PLoS Pathogens · 2008 · 354 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

SREBP Pathway Responds to Sterols and Functions as an Oxygen Sensor in Fission Yeast

Adam L. Hughes, Bridget L. Todd, Peter J. Espenshade · Cell · 2005 · 324 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10