Concepedia

Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate

Jesica Swanstrom, Sandra Henein, Jessica A. Plante, Boyd L. Yount, Douglas G. Widman, Emily N. Gallichotte, Hansi Dean, Jorge E. Osorio, Charalambos D. Partidos, Aravinda M. de Silva,

The Journal of Infectious Diseases · 2018 · 29 citations · 30 references

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Abstract

Here we provide qualitative measures of the magnitude and epitope specificity of the nAb responses to TDV. This information will be useful for understanding the performance of TDV in clinical trials and for identifying correlates of protective immunity.

References

30

The global distribution and burden of dengue

Samir Bhatt, Peter W. Gething, Oliver J. Brady et al. · Nature · 2013 · 9.8K citations · Full text

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Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

Sri Rezeki Hadinegoro, José Luis Arredondo-Garcı́a, Maria Rosario Capeding et al. · New England Journal of Medicine · 2015 · 1.1K citations · Full text

A Prospective Study of Dengue Infections in Bangkok

Donald S. Burke, Ananda Nisalak, David E. Johnson et al. · American Journal of Tropical Medicine and Hygiene · 1988 · 825 citations

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The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

Martina Beltramello, Katherine L. Williams, Cameron P. Simmons et al. · Cell Host & Microbe · 2010 · 590 citations · Full text

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Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

Ruklanthi de Alwis, Scott A. Smith, Nicholas P. Olivarez et al. · Proceedings of the National Academy of Sciences · 2012 · 391 citations · Full text

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