Interleukin 6, osteoprotegerin, sRANKL and bone metabolism in inflammatory bowel diseases

Abstract

The incidence of osteopenia and osteoporosis in patients with IBD is high and increases with the duration of the disease and the number of hospitalizations. Patients with CD are at a higher risk of skeletal pathology than patients with UC. IL-6 can modulate bone mineral density in the femoral neck especially in the course of CD.