Military Medicine · 2018 · 19 citations · 20 references
This pilot study demonstrated a trend towards decreased vasopressor dose, and decreased benzodiazepine and opiate use when ketamine is used as the sole sedative. The limitations to our study include a small sample size and those inherent in using a retrospective control group. Our findings should be further explored in a large, randomized prospective study.
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Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.7K citations · Full text
R. Phillip Dellinger, Mitchell M. Levy, Andrew Rhodes et al. · Critical Care Medicine · 2013 · 9.7K citations
Critical Care Management, Critical Care Medicine, Severe Sepsis +13
Trial of Early, Goal-Directed Resuscitation for Septic Shock
Paul Mouncey, Tiffany M. Osborn, G. Sarah Power et al. · New England Journal of Medicine · 2015 · 1.5K citations · Full text