Concepedia

Hemorrhagic shock alters fracture callus composition and activates the IL6 and RANKL/OPG pathway in mice

Katrin Bundkirchen, Christian Macke, Nina Angrisani, Luisa Marilena Schäck, Sandra Noack, Michael Fehr, Christian Krettek, Claudia Neunaber

The Journal of Trauma: Injury, Infection, and Critical Care · 2018 · 18 citations · 18 references

DOI

Abstract

Hemorrhagic shock has a retarding effect on fracture healing in the early phase of fracture healing and leads to activation of the IL6 and RANKL/OPG signaling pathways.

References

18

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young‐Yun Kong, Ulrich Feige, Iidiko Sarosi et al. · Nature · 1999 · 1.9K citations

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Impaired Fracture Healing in the Absence of TNF-α Signaling: The Role of TNF-α in Endochondral Cartilage Resorption

L. C. Gerstenfeld, T-J Cho, Tamiyo Kon et al. · Journal of Bone and Mineral Research · 2003 · 429 citations

Predictors of Reoperation Following Operative Management of Fractures of the Tibial Shaft

Mohit Bhandari, Paul Tornetta, Sheila Sprague et al. · Journal of Orthopaedic Trauma · 2003 · 243 citations

Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis

Kalle Söderström, Emily Stein, Paula Colmenero et al. · Proceedings of the National Academy of Sciences · 2009 · 183 citations · Full text

Distinct Effects of IL-6 Classic and Trans -Signaling in Bone Fracture Healing

Katja Prystaz, Kathrin Kaiser, Anna Kovtun et al. · American Journal Of Pathology · 2017 · 130 citations · Full text

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