Direct Deuteration of Acrylic and Methacrylic Acid Derivatives Catalyzed by Platinum on Carbon in Deuterium Oxide

Abstract

Abstract The platinum on carbon (Pt/C)‐catalyzed deuteration of acrylic and methacrylic acid derivatives in deuterium oxide (D 2 O) efficiently proceeded to give the corresponding acrylic acid‐ d 3 and methacrylic acid‐ d 5 derivatives. The olefinic functionality, as well as the methyl group on the unsaturated functionality of the substrate, were satisfactorily deuterated via the hydrogen (H)‐deuterium (D) exchange reaction. The obtained deuterated compounds are useful building blocks and efficiently converted to the corresponding desired products including a polymer without the degradation of the original deuterium contents. magnified image